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Our research articles

Research articles

To see the full list of our publications see: 

https://scholar.google.com/citations?hl=iw&user=KuztO90AAAAJ&view_op=list_works&sortby=pubdate

Selected Recent papers:

 

Maternal supplementation with n-3 fatty acids affects placental lipid metabolism, inflammation, oxidative stress the endocannabinoid system, and the neonate cytokine concentration in dairy cows.

dos Santos Silva P, Kra G, Butenko Y, Daddam JR, Levin Y, Zachut, M. Journal of Animal Science and Biotechnology. 2024; In Press.

Plant polyphenol extract supplementation affects performance, welfare, and the Nrf2-oxidative stress response in adipose tissue of heat-stressed dairy cows.

Daddam JR, Daniel D, Kra G, Pelech I, Portnick Y, Moallem U, Lavon Y, Zachut M. J Dairy Sci. 2023 Dec;106(12):9807-9821. doi: 10.3168/jds.2023-23549. Epub 2023 Aug 23.PMID: 37641328 Free article.

 

Alpha-linolenic acid modulates systemic and adipose tissue-specific insulin sensitivity, inflammation, and the endocannabinoid system in dairy cows.

Kra G, Daddam JR, Moallem U, Kamer H, Mualem B, Levin Y, Kočvarová R, Nemirovski A, Contreras AG, Tam J, Zachut M. Sci Rep. 2023 Mar 31;13(1):5280. doi: 10.1038/s41598-023-32433-7.PMID: 37002295 Free PMC article.

 

Cannabinoid-1 receptor activation modulates lipid mobilization and adipogenesis in the adipose tissue of dairy cows.

Myers MN, Abou-Rjeileh U, Chirivi M, Parales-Girón J, Lock AL, Tam J, Zachut M, Contreras GA. J Dairy Sci. 2023 May;106(5):3650-3661. doi: 10.3168/jds.2022-22556. Epub 2023 Mar 10.PMID: 36907764 Free article.

 

Glucose-6-Phosphate Dehydrogenase Activity in Milk May Serve as a Non-Invasive Metabolic Biomarker of Energy Balance in Postpartum Dairy Cows.

Hod A, Daddam JR, Kra G, Kamer H, Portnick Y, Moallem U, Zachut M. Metabolites. 2023 Feb 20;13(2):312. doi: 10.3390/metabo13020312.PMID: 36837930 Free PMC article.

 

Modulating immunometabolism in transition dairy cows: the role of inflammatory lipid mediators.

Zachut M, Tam J, Contreras GA. Anim Front. 2022 Oct 14;12(5):37-45. doi: 10.1093/af/vfac062. eCollection 2022 Oct.PMID: 36268169 Free PMC article. No abstract available.

 

Effects of omega-3 supplementation on components of the endocannabinoid system and metabolic and inflammatory responses in adipose and liver of peripartum dairy cows.

Kra G, Daddam JR, Moallem U, Kamer H, Kočvarová R, Nemirovski A, Contreras GA, Tam J, Zachut M. J Anim Sci Biotechnol. 2022 Oct 2;13(1):114. doi: 10.1186/s40104-022-00761-9.PMID: 36183098 Free PMC article.

 

Proteomic analysis of adipose tissue revealing differentially abundant proteins in highly efficient mid-lactating dairy cows.

Ben Meir YA, Daddam JR, Kra G, Kamer H, Portnick Y, Levin Y, Zachut M. Sci Rep. 2022 Jun 13;12(1):9721. doi: 10.1038/s41598-022-13964-x.PMID: 35697844 Free PMC article.

 

Effects of Environmental Heat Load on Endocannabinoid System Components in Adipose Tissue of High Yielding Dairy Cows.

Kra G, Daddam JR, Moallem U, Kamer H, Ahmad M, Nemirovski A, Contreras GA, Tam J, Zachut M. Animals (Basel). 2022 Mar 21;12(6):795. doi: 10.3390/ani12060795.PMID: 35327191 Free PMC article.

 

Proteome dataset of peripheral blood mononuclear cells in postpartum dairy cows supplemented with different sources of omega-3 fatty acids.

Kra G, Nemes-Navon N, Daddam JR, Livshits L, Jacoby S, Levin Y, Zachut M, Moallem U. Data Brief. 2022 Jan 4;40:107785. doi: 10.1016/j.dib.2021.107785. eCollection 2022 Feb.PMID: 35036486 Free PMC article.

 

Proteome dataset of liver from dairy cows experiencing negative or positive energy balance at early lactation.

Swartz TH, Moallem U, Kamer H, Kra G, Levin Y, Mamedova LK, Bradford BJ, Zachut M. Data Brief. 2021 Oct 27;39:107517. doi: 10.1016/j.dib.2021.107517. eCollection 2021 Dec.PMID: 34765708 Free PMC article.

 

Proteomic analysis of peripheral blood mononuclear cells and inflammatory status in postpartum dairy cows supplemented with different sources of omega-3 fatty acids.

Kra G, Nemes-Navon N, Daddam JR, Livshits L, Jacoby S, Levin Y, Zachut M, Moallem U. J Proteomics. 2021 Aug 30;246:104313. doi: 10.1016/j.jprot.2021.104313. Epub 2021 Jul 1.PMID: 34216809

 

Antioxidant Resveratrol Increases Lipolytic and Reduces Lipogenic Gene Expression under In Vitro Heat Stress Conditions in Dedifferentiated Adipocyte-Derived Progeny Cells from Dairy Cows.

Kra G, Daddam JR, Gabay H, Yosefi S, Zachut M. Antioxidants (Basel). 2021 Jun 3;10(6):905. doi: 10.3390/antiox10060905.PMID: 34205039 Free PMC article.

 

Characterization of the liver proteome in dairy cows experiencing negative energy balance at early lactation.

Swartz TH, Moallem U, Kamer H, Kra G, Levin Y, Mamedova LK, Bradford BJ, Zachut M. J Proteomics. 2021 Aug 30;246:104308. doi: 10.1016/j.jprot.2021.104308. Epub 2021 Jun 18.PMID: 34153542

Review papers

Review: Phenotypic and molecular evidence of inter- and trans-generational effects of heat stress in livestock mammals and humans.

Laporta J, Khatib H, Zachut M.Animal. 2024 Feb 29:101121. doi: 10.1016/j.animal.2024.101121. Online ahead of print.PMID: 38531705 Free article. Review.

 

Symposium review: Mechanistic insights into adipose tissue inflammation and oxidative stress in periparturient dairy cows.

Zachut M, Contreras GA.J Dairy Sci. 2022 Apr;105(4):3670-3686. doi: 10.3168/jds.2021-21225. Epub 2022 Feb 10.PMID: 35151484 Free article. Review.

 

Domestic animal proteomics in the 21st century: A global retrospective and viewpoint analysis.

Almeida AM, Ali SA, Ceciliani F, Eckersall PD, Hernández-Castellano LE, Han R, Hodnik JJ, Jaswal S, Lippolis JD, McLaughlin M, Miller I, Mohanty AK, Mrljak V, Nally JE, Nanni P, Plowman JE, Poleti MD, Ribeiro DM, Rodrigues P, Roschitzki B, Schlapbach R, Starič J, Yang Y, Zachut M.J Proteomics. 2021 Jun 15;241:104220. doi: 10.1016/j.jprot.2021.104220. Epub 2021 Apr 7.PMID: 33838350 Review.

 

A proposed modulatory role of the endocannabinoid system on adipose tissue metabolism and appetite in periparturient dairy cows.

Myers MN, Zachut M, Tam J, Contreras GA.J Anim Sci Biotechnol. 2021 Mar 5;12(1):21. doi: 10.1186/s40104-021-00549-3.PMID: 33663611 Free PMC article. Review.

 

The application of omics in ruminant production: a review in the tropical and sub-tropical animal production context.

Ribeiro DM, Salama AAK, Vitor ACM, Argüello A, Moncau CT, Santos EM, Caja G, de Oliveira JS, Balieiro JCC, Hernández-Castellano LE, Zachut M, Poleti MD, Castro N, Alves SP, Almeida AM.J Proteomics. 2020 Sep 15;227:103905. doi: 10.1016/j.jprot.2020.103905. Epub 2020 Jul 24.PMID: 32712373 Review.

 

Biomarkers of fitness and welfare in dairy cattle: healthy productivity.

Zachut M, Šperanda M, de Almeida AM, Gabai G, Mobasheri A, Hernández-Castellano LE.J Dairy Res. 2020 Feb;87(1):4-13. doi: 10.1017/S0022029920000084.PMID: 32114995 Review.

 

Biomarkers of fitness and welfare in dairy animals: healthy living.

de Almeida AM, Zachut M, Hernández-Castellano LE, Šperanda M, Gabai G, Mobasheri A.J Dairy Res. 2019 Nov;86(4):379-387. doi: 10.1017/S0022029919000803. Epub 2019 Nov 20.PMID: 31744555 Review.

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